Wrinkles and lines aren’t the only signs of aging. Over time, the cheeks flatten, and the skin may begin to sag. They are caused by a natural loss of volume in the cheek area, or what the experts call age-related midface volume loss. JUVÉDERM VOLUMA® XC adds the amount to correct age-related volume loss in the cheeks to help create a more youthful appearance. When treated again after two years, patients needed less product to achieve their results.